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これまで研究開発と新たな発見
論文一覧
2024年 | Lipid and Transcriptional Regulation in a Parkinson’s Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen-Based Nanomedicines. Wu Y, Wang J, Deng Y, Angelov B, Fujino T, Hossain S, Angelova A. Adv. Healthcare Mater. 2304588, 2024 |
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2023年 | Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies. Wu Y, Angelov B, Deng Y, Fujino T, Hossain S, Drechsler M, Angelova A. Commun Chem 6 : 241, 2023 |
2023年 | Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies. Wu Y, Angelov B, Deng Y, Fujino T, Hossain S, Drechsler M, Angelova A. Commun Chem 6 : 241, 2023 |
Orally Administered Plasmalogens Alleviate Psycho-behavioral Parameters in Patients with Depressive Disorder: An Observational Study. Obo T, Obo M, Fukuchi M, Sasuga Y, Fujino T, Kono S. Mega Journal of Case Reports, 2023 | |
Plasmalogens inhibit neuroinflammation and promote cognitive function. S.Hossain,et,al. Brain Res Bull 192:56-61,2023 | |
2022年 | Plasmalogens, the vinyl ether-linked glycerophospholipids, enhance learning and memory by regulating brain-derived neurotrophic factor. Hossain S, Mawatari S, Fujino T. Front Cell Dev Biol 2022, 10:828282. |
Plasmalogen-mediated activation of GPCR21 regulates cytolyty of NK cells against the target cells. S.Hossain,et al. J Immunol 209:310-325,2022 | |
Decreases of ethanolamine plasmalogen and phosphatidylcholine in erythrocyte are a common phenomenon in Alzheimer’s,and coronary artery diseases. S.Mawatari,et al. Brain Res Bull 189:5-10,2022 | |
2021年 | Plasmalogen attenuates LPS-induced ICAM-1 expression in endothelial cell line. Kanda R, Iwasaki K, Yihao P, Umeda M, Fujino T, Kawazoe T. J Osaka Dent Univ 2021, 5:179-185. |
2020年 | Improvement of blood plasmalogens and clinical symptoms in Parkinson’s disease by oral administration of ether phospholipids: a preliminary report. S.Mawatari,et al. Parkinsons Dis 2020:2671070,2020 |
Identification of plasmalogens in Bifidobacterium longum,but not in Bifidobacterium animalis. S.Mawatari,et al. J Sci Rep 10:427,2020 | |
2019年 | Effects of plasmalogen on patients with moderate-to-severe Alzheimer’s disease and blood plasmalogen changes: a multi-center,open-label study. T.Fujino,et al. J Alzheimers Dis Parkinsonism 9:474,2019 |
2018年 | Oral ingestion of plasmalogens can attenuate the LPS-induced memory loss and microglial activation. MS.Hossain,et al. Biochem Biophys Res Commun 496:1033-1039,2018 |
Enzymatic measurement of other phospholipids in human plasma after hydrolysis of plasma with phospholipase A1. S.Mawatari,at al. Pract Lab Med 10:44-51,2018 |
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